Skin Rejuvenation

Polynucleotides

DNA-Based Skin Regeneration & Bio-Stimulation

Polynucleotides

About This Treatment

Polynucleotides are purified fragments of DNA, typically derived from salmon or trout sperm, that have emerged as one of the most sophisticated regenerative injectables in modern aesthetic medicine. Unlike fillers, which add volume, or bio-stimulators, which add framework, polynucleotides repair and regenerate tissue at a cellular level — improving skin quality, elasticity, and hydration from within.

Once injected, polynucleotide fragments stimulate fibroblast activity, enhance cellular turnover, and promote the synthesis of new collagen and elastin. They also exert powerful anti-inflammatory and antioxidant effects, making them especially effective for delicate areas such as the under-eyes, neck, and hands. The result is skin that looks visibly healthier, firmer, and more luminous over a course of treatments.

At Alpha Medical Limassol, polynucleotide therapy is a cornerstone of our regenerative aesthetic protocols. We also offer the treatment at our partner clinics in Tel Aviv and Dubai, with the same physician-led standards across every location.

Key Benefits

Deep Skin Regeneration

Repairs damaged skin at the cellular level for improvements that go far beyond surface treatments.

Under-Eye Rejuvenation

One of the few treatments safe and effective for delicate under-eye skin — reduces dark circles and crepiness.

Collagen & Elastin Stimulation

Activates fibroblasts to rebuild the skin's structural framework from within.

Anti-Inflammatory

Calms reactive, inflamed skin and supports recovery from laser and energy-based treatments.

Hydration & Radiance

Deeply hydrates at the dermal level for glowing, plump, elastic skin.

Suitable for All Skin Types

Biocompatible and exceptionally well tolerated with minimal risk of reaction.

The Treatment Process

1

Consultation & Skin Analysis

Your practitioner evaluates your skin quality, concerns, and goals to build a bespoke polynucleotide protocol.

2

Preparation

The treatment area is cleansed and topical anaesthetic is applied for comfort, particularly around the eyes.

3

Precise Injection

Using ultra-fine needles or cannulas, small aliquots of polynucleotide gel are placed into the treatment zone.

4

Recovery & Follow-Up

Minimal downtime. A typical course involves 3-4 sessions spaced 3-4 weeks apart, with maintenance every 6-9 months.

Ideal For Treating

Tired, dull or dehydrated skin
Under-eye dark circles and crepiness
Early skin laxity on face and neck
Fine lines and loss of elasticity
Post-procedure healing and skin recovery
Acne scarring and textural irregularity
Neck and décolletage rejuvenation
Hand rejuvenation
Patients seeking natural, regenerative results without volume change

Where We Practice

Polynucleotides Across Three Clinics

Alpha Medical delivers Polynucleotides at the same physician-led standard across all our locations. Our flagship clinic is in Limassol, Cyprus, with partner clinics in Tel Aviv and Dubai for patients who travel between regions.

Flagship

Limassol, Cyprus

Our Limassol clinic is the primary centre for Polynucleotides, serving patients from across Cyprus — including Nicosia, Larnaca, and Paphos — as well as international patients.

Book in Limassol →

Partner Clinic

Tel Aviv, Israel

Polynucleotides is also available at our Tel Aviv location, with the same physician-led protocols and clinical standards.

Enquire about Tel Aviv →

Partner Clinic

Dubai, UAE

Our Dubai location delivers Polynucleotides under the same Alpha Medical standards for patients based in or travelling through the Gulf.

Enquire about Dubai →

Frequently Asked Questions

Additional Information

Request More Information About Polynucleotides

Leave your details and our team will send you an introductory overview by email, then reach out personally. You are welcome to contact us directly on WhatsApp at any time.

Polynucleotides

Additional Information About Polynucleotides

Enter your details and we will send you an introductory guide about Polynucleotides by email. Our clinical team will follow up with you personally.

Prefer to chat now? Message us directly on WhatsApp.

Ready to Begin?

Schedule a private consultation with our skin specialists to discuss how Polynucleotides can help you achieve your aesthetic goals.

Medical Disclaimer: Results vary between individuals. All treatments are performed by qualified medical professionals. A consultation is required to assess your suitability for any procedure. The information on this page is for educational purposes and does not constitute medical advice.