Hormone HealthCyprus6 min read

Migraine Botox in Cyprus: Evidence-Based Chronic Migraine Relief

Chronic migraine sufferers in Cyprus now have access to one of the most effective evidence-based preventative treatments available: therapeutic Botox using the PREEMPT protocol.

Medically reviewed by Alpha Medical Medical Team
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Migraine Botox in Cyprus: Evidence-Based Chronic Migraine Relief

For patients who live with chronic migraine — 15 or more headache days per month — therapeutic Botox is one of the most effective preventative treatments available. At Alpha Medical Cyprus, we administer Botox for chronic migraine using the internationally validated PREEMPT protocol.

This article explains what migraine Botox is, who it is for, and why it is different from the cosmetic Botox most people know.

Chronic Migraine vs Episodic Migraine

Therapeutic Botox is specifically indicated for chronic migraine — meaning 15 or more headache days per month, with at least 8 of them migrainous, for at least 3 months. Patients with fewer days (episodic migraine) are usually better managed with acute and preventative medications first.

The PREEMPT Protocol

The PREEMPT protocol is the globally validated standard for migraine Botox. It uses 155-195 units of botulinum toxin across 31-39 precise injection points covering the forehead, temples, back of the head, neck and shoulders. The full treatment takes 15-20 minutes and is repeated every 12 weeks.

Why It Works

Botulinum toxin modulates the release of pain-related neurotransmitters and calms the muscular and neural triggers that contribute to migraine generation. Clinical studies consistently show significant reduction in migraine days and intensity across 2-3 treatment cycles.

Ready to take the next step? Book a consultation at our contact page — or request an introductory Migraine Treatment guide below.

Peer-Reviewed References

Clinical Evidence & Further Reading

This article is grounded in peer-reviewed medical literature. The following PubMed-indexed publications support the clinical claims made above and are recommended for patients and clinicians who wish to explore the topic further.

  1. Dodick DW, Turkel CC, DeGryse RE, Aurora SK, Silberstein SD, Lipton RB, et al. OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program. Headache. 2010. PMID: 20487038.
  2. Aurora SK, Dodick DW, Turkel CC, DeGryse RE, Silberstein SD, Lipton RB, et al. OnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 1 trial. Cephalalgia. 2010. PMID: 20647170.

Migraine Treatment

Additional Information About Migraine Treatment

Enter your details and we will send you an introductory guide about Migraine Treatment by email. Our clinical team will follow up with you personally.

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Frequently Asked Questions

Migraine Botox Cyprus | PREEMPT Protocol | Alpha Medical Limassol