Hormone HealthLimassol5 min read

Polynucleotides in Limassol: What to Expect at Alpha Medical

A practical, patient-focused guide to polynucleotide treatment at Alpha Medical Limassol — what to expect on treatment day, what the results look like, and how to plan your course.

Medically reviewed by Alpha Medical Medical Team
on
Polynucleotides in Limassol: What to Expect at Alpha Medical

If you have read about polynucleotide therapy and want to understand exactly what it looks like in practice, this guide walks you through the process at our Limassol clinic — from consultation to final result.

We also regularly see patients from Nicosia, Larnaca and Paphos, as well as international patients from Israel, the Gulf, and Europe, who come specifically to Limassol for polynucleotide therapy.

The Consultation

Every polynucleotide treatment at Alpha Medical begins with a proper consultation. Your physician examines your skin, discusses your concerns and goals, and confirms polynucleotide therapy is the right tool for you — versus profhilo, fillers, microneedling, or a combination.

Treatment Day

On treatment day, your skin is cleansed and topical anaesthetic is applied for 15-20 minutes — particularly important for under-eye work. The polynucleotide gel is then injected using ultra-fine needles or cannulas across the target areas in small, precise aliquots. The treatment itself takes 15-30 minutes.

After the Treatment

Mild swelling and small visible injection points are normal for 24-48 hours. Most patients return to work the same day or the next morning. Full results build gradually — immediate glow and hydration in the first week, structural improvements in elasticity and texture over 2-3 months.

Typical Course at Our Limassol Clinic

A full course is typically 3-4 sessions spaced 3-4 weeks apart, followed by maintenance every 6-9 months. Many patients combine polynucleotides with profhilo, mesotherapy, or microneedling for enhanced results.

Ready to take the next step? Book a consultation at our contact page — or request an introductory Polynucleotides guide below.

Peer-Reviewed References

Clinical Evidence & Further Reading

This article is grounded in peer-reviewed medical literature. The following PubMed-indexed publications support the clinical claims made above and are recommended for patients and clinicians who wish to explore the topic further.

  1. Squadrito F, Bitto A, Irrera N, Pizzino G, Pallio G, Minutoli L, Altavilla D. Pharmacological Activity and Clinical Use of PDRN. Front Pharmacol. 2017. PMID: 28588486.
  2. Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M, et al. Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine. J Cosmet Dermatol. 2021. PMID: 33205883.

Polynucleotides

Additional Information About Polynucleotides

Enter your details and we will send you an introductory guide about Polynucleotides by email. Our clinical team will follow up with you personally.

Prefer to chat now? Message us directly on WhatsApp.

Frequently Asked Questions

Polynucleotides Limassol | Skin Regeneration Clinic | Alpha Medical