Hormone HealthCyprus6 min read

Polynucleotides in Cyprus: The Regenerative Injectable Changing Aesthetic Medicine

Polynucleotides are emerging as one of the most sophisticated regenerative injectables available in Cyprus. Here is what patients need to know.

Medically reviewed by Alpha Medical Medical Team
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Polynucleotides in Cyprus: The Regenerative Injectable Changing Aesthetic Medicine

In the last two years, polynucleotide therapy has quietly become one of the most in-demand regenerative treatments in Cyprus. Unlike hyaluronic acid fillers, which add volume, polynucleotides work at the cellular level — repairing and regenerating skin from within. The result is a treatment that improves skin quality rather than reshaping it.

At Alpha Medical in Cyprus, we have seen polynucleotides become a cornerstone of our regenerative protocols, with patients travelling from Limassol, Nicosia, Larnaca and Paphos — and internationally from the UK, Israel and the Gulf — specifically for this treatment.

What Are Polynucleotides?

Polynucleotides are highly purified fragments of DNA, typically extracted from salmon or trout. When injected into the skin, they stimulate fibroblast activity and promote the synthesis of new collagen and elastin. They also have powerful anti-inflammatory and antioxidant effects — which is why they are so effective for delicate areas like the under-eyes.

Why Cyprus Patients Are Choosing Polynucleotides

Cyprus patients are increasingly focused on natural, regenerative results rather than dramatic volumetric change. Polynucleotides deliver exactly that: improved skin quality, reduced crepiness, better elasticity, and a genuine glow — without adding volume or changing facial contours.

  • Safe and effective for under-eye treatment
  • Repairs damaged and aging skin at a cellular level
  • Suitable for patients of all skin types
  • Excellent alongside microneedling, profhilo, and laser
  • Minimal downtime — return to normal activities the same day

The Alpha Medical Approach

At our Cyprus clinic, polynucleotide therapy is physician-led. Your treatment is preceded by a proper skin assessment, and a course of 3-4 sessions spaced 3-4 weeks apart is usually recommended. We also offer polynucleotide treatments at our Tel Aviv and Dubai clinics for patients who travel.

Ready to take the next step? Book a consultation at our contact page — or request an introductory Polynucleotides guide below.

Peer-Reviewed References

Clinical Evidence & Further Reading

This article is grounded in peer-reviewed medical literature. The following PubMed-indexed publications support the clinical claims made above and are recommended for patients and clinicians who wish to explore the topic further.

  1. Squadrito F, Bitto A, Irrera N, Pizzino G, Pallio G, Minutoli L, Altavilla D. Pharmacological Activity and Clinical Use of PDRN. Front Pharmacol. 2017. PMID: 28588486.
  2. Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M, et al. Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine. J Cosmet Dermatol. 2021. PMID: 33205883.

Polynucleotides

Additional Information About Polynucleotides

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Frequently Asked Questions

Polynucleotides Cyprus | Salmon DNA Skin Regeneration | Alpha Medical